For orders over 1.000 MKD
Products from renowned brands with top quality
02 324 6000 | info@trimeks.com.mk
1000 mcg / 90 tabs 1.640 ден
1000 mg / 180 tabs 1.730 ден
Flush Free Niacin
250 mg / 90 vcaps
1.050 ден
Brand | |
---|---|
Индикации | Cardiovascular health |
Nutritional Health
Niacin (Vitamin B-3) is an essential B-Complex vitamin. Flush-free Niacin contains Inositol Hexanicotinate, a form of Niacin that contains six molecules of niacin linked to a single inositol molecule. It is slowly broken down in the body to yield free niacin and inositol. This gradual release of Niacin allows for true Niacin activity without the characteristic Niacin flush that many people cannot tolerate.
Inositol Hexanicotinate is a stable, non-flushing source of Niacin. This superior source of Niacin works to reduce the common “niacin-flush” problems associated with high doses of Niacin supplements.
SUPPLEMENT FACTS
Serving Size: | 2 Capsules | |
---|---|---|
Servings Per Container: | 45 | |
Amount per Serving | % Daily Value | |
Folate [1,000 mcg (6S)-5-MTHF**]Niacin (Vitamin B-3) (from 640 mg of Inositol Hexanicotinate) | 500 mg | 3125% |
Inositol (from 640 mg of Inositol Hexanicotinate) | 135 mg |
Other Ingredients: Rice Flour, Cellulose (capsule), Cellulose Powder, Stearic Acid (vegetable source), Guar Gum, Silica and Magnesium Stearate (vegetable source).
Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
SUGGESTED USAGE
Take 2 capsules daily as needed, with food.
CAUTION
For adults only. Consult physician if pregnant/nursing, taking medication, or have a medical condition (liver problems, stomach ulcers, diabetes, gout, etc.). Keep out of reach of children.
Natural color variation may occur in this product.
Store in a cool, dry place after opening.
MORE INFORMATION
Flush free forms of niacin
It is well documented that niacinamide (nicotinamide) does not cause a niacin flush, nor does inositol hexanicotinate, which is commonly sold as flush-free niacin.2,3,4 This means that these forms should probably not be (but are) included in the UL for niacin (nicotinic acid).
In many NOW® products, including multivitamins and B-complex vitamins, only the flush-free forms niacinamide (nicotinamide) and inositol hexanicotinate are actually included in the formulas. A few formulas contain the co-enzyme form of niacin, called NAD, in small amounts, and this form is also considered to be safe and flush-free.
ChromeMate® is a unique form of biologically active niacin-bound chromium called chromium nicotinate or chromium polynicotinate that dramatically increases the effectiveness of chromium. NOW uses this form of chromium in several products, and it has a proven safety record. A serving of ChromeMate® provides 200 mcg of elemental chromium and 1.1 mg of niacin, a relatively low level supplying only 5.5% of the Daily Value.
Niacin Flushing
The niacin flush consists of skin reddening, itching and/or burning starting 10 to 20 minutes after oral ingestion and lasting about 60 to 90 minutes. Although most patients experience tolerance to the flush within a week, as many as 40% of patients started on nicotinic acid eventually discontinue therapy, even when started on sustained release formulations. The niacin flush can also be largely avoided by taking aspirin at least 30 minutes before niacin, so those who take aspirin daily may be somewhat protected from this uncomfortable side effect even when taking true niacin. There is some evidence that the risk of developing liver toxicity from very high doses of niacin could possibly be lowered by supplementing with a methyl donor, such as TMG (betaine), to prevent depletion of S-adenosylmethionine (SAM-e or SAMe).
Niacin in NOW® products
Based on references, the forms and amounts of niacin present in most NOW supplements should not cause any significant adverse effects when used as directed, even when taking those forms of niacin in potencies above the UL, such as those found in B-50 Complex or ADAM™(Tablets, Softgels, Veg Capsules). Higher amounts than recommended on a product label should only be used as directed by a health professional, who should monitor the person for symptoms of toxicity that could occur at much higher levels. Adverse effects (other than flushing) have occurred at relatively high doses of 1,500 mg/day for niacin and 3,000 mg/day for niacinamide, far above the 35 mg/day UL set for all forms of niacin.
All forms of niacin are not created equal from a scientific viewpoint. It is important, from an individual biochemistry and health perspective, to ensure that various forms of niacin are available in potencies above the UL, which was set largely for people to avoid the niacin flush, along with information on their safe use.