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Methyl Folate
1000 mcg / 90 tabs
1.640 ден
Brand | |
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Индикации | Cardiovascular health, Nervous system and mental health, Женско здравје, Расположение, стрес и сон |
Co-Enzyme B Vitamin
Metabolically Active Folate
Superior Bioavailability
Methylfolate is the biologically active, naturally occurring form of folate that is used for fundamental body functions like normal cell division and the synthesis of neurotransmitters and DNA. Unlike regular folic acid, Methylfolate has been shown to penetrate the blood-brain barrier, where it helps to support neurological health. Quatrefolic® is a patented form of Methylfolate that has demonstrated bioavailability superior to that of folate from dietary sources.
SUPPLEMENT FACTS
Serving Size: | 1 Tablet | |
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Servings Per Container: | 90 | |
Amount per Serving | % Daily Value | |
Folate [1,000 mcg (6S)-5-MTHF**][from Quatrefolic® (6S)-5-MTHF** Glucosamine Salt] | 1,667 mcg DFE | 417% |
Other Ingredients: Cellulose, Stearic Acid (vegetable source) and Silica.
Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
SUGGESTED USAGE
Take 1 tablet daily with a meal.
Quatrefolic® is a registered trademark of Gnosis S.p.A. and protected by U.S. Patent 7,947,662.
**MTHF = Methyltetrahydrofolate
CAUTION
For adults only. The elderly and individuals with conditions that may impair vitamin B-12 absorption should frequently check vitamin B-12 status when taking this product as high-dose folic acid may mask vitamin B-12 deficiency. Consult physician if pregnant/nursing, taking medication (especially phenobarbital, phenytoin, primidone, and methotrexate), or have a medical condition (especially any condition involving nutrient malabsorption). Keep out of reach of children.
Store in a cool, dry place after opening.
MORE INFORMATION
Methyl B-12 10,000 mcg – Pharmacokinetic (pK) Study
Bioavailability Study
Methyl B-12 is a co-enzyme form of vitamin B-12 (cobalamin) necessary for the production of energy from fats and proteins. It plays a critical role in DNA synthesis, as well as in homocysteine metabolism. Three healthy adult volunteers 22 to 58 years old participated in a clinical trial to study the bioavailability of Methyl B-12, a dietary supplement from NOW® (item # 0501). Serum cobalamin was measured at baseline, and again at 1, 3, 7 and 24 hours following oral administration of one lozenge providing 10,000 mcg of vitamin B-12.
Results
Average cobalamin level was increased one hour after administration, and peaked seven hours following administration, reaching 54% above the baseline level. Average cobalamin concentration remained 17% above the baseline level 24 hours post-supplementation. This study confirms the exceptional bioavailability of NOW® Methyl B-12.
Average serum cobalamin level before, and at 1, 3, 7 and 24 hours following a single administration of one Methyl B-12 lozenge (NOW®, Bloomingdale, IL; item # 0501) providing 10,000 mcg of methylcobalamin in healthy adult volunteers.